Addition of simvastatin to carvedilol non responders: A new pharmacological therapy for treatment of portal hypertension

Table 3 Hemodynamic parameters (mean) of studied population

Hemodynamic parameters	Baseline	Post chronic carvedilol (3 mo)	Post simvastatin
CO (L/min)	7.525 ± 0.19	6.38 ± 0.13	6.195 ± 0.17
HR (beats/min)	79.45 ± 2.50	57.45 ± 2.44	55.053 ± 1.67
MAP (mmHg)	89.53 ± 2.42	75.54 ± 1.97	74.500 ± 1.48
FHVP (mmHg)	8.28 ± 1.85	9.45 ± 1.90	10.086 ± 1.68
WHPG (mmHg)	25.08 ± 2.55	22.04 ± 2.56	23.114 ± 2.32
HVPG (mmHg)	16.75 ± 2.12	12.60 ± 2.24	13.029 ± 1.56

CO: Cardiac output; HR: Heart rate; MAP: Mean arterial pressure; FHVP: Free hepatic venous pressure; WHPG: Wedged hepatic venous pressure gradient; HVPG: Hepatic venous pressure gradient.