Reverse time-dependent effect of alphafetoprotein and disease control on survival of patients with Barcelona Clinic Liver Cancer stage C hepatocellular carcinoma

Table 4 Characteristics of the 5 patients with long-survival (median 63.3 mo)

PT	Gender	Age	Etiology	PS	Child-Pugh	AFP > 200 ng/mL	No. of nodules	Maximum size	Macrovascular invasion	Extrahepatic spread	Diabetes	Pre-BCLC C treatments	Post-BCLC C treatments	Best response	DC	Survival (mo)	Status
PT3	M	65	HBV	1	A	No	Infiltrating	Infiltrating	Yes	No	No	None	Sorafenib	CR	Yes	79.4	Alive
PT10	M	73	HCV	1	A	No	> 3	18	No	No	No	TACE, resection, sorafenib	Second line systemic agent, DSM-TACE (2)	SD	Yes	63.3	Alive
PT27	M	58	HBV	2	B	No	2	19	No	No	No	RFA, TACE	LT	CR	Yes	67.1	Alive
PT53	M	63	Alcohol	1	B	No	> 3	50	No	No	No	None	TACE (4), TACE + RFA (1), LT	CR	Yes	58.9	AliVe
PT54	M	65	HCV	0	A	No	Single	40	Yes	No	Yes	None	TARE (2)	SD	Yes	38.1	Alive

HBV: Hepatitis B virus; HCV: Hepatitis C virus; PS: Performance status; BCLC: Barcelona Clinic Liver Cancer; AFP: Alphafetoprotein; TACE: Transarterial chemoembolization; RFA: Radiofrequency ablation; DSM-TACE: Degradable starch microspheres transarterial chemoembolization; LT: Liver transplant; TARE: Transarterial radioembolization; CR: Complete response; SD: Stable disease; DC: Disease control.