Recent trends in liver transplantation for alcoholic liver disease in the United States

Table 2 Temporal trends in characteristics of alcoholic liver disease liver transplant recipients

	2002	2003	2004	2005	2006	2007	2008	2009	2010	2011	2012	2013	2014	2015	P value
n (% annual)	553 (12.8%)	597 (12.8%)	628 (12.4%)	688 (13.0%)	695 (12.7%)	660 (12.3%)	578 (11.1%)	608 (11.6%)	619 (11.7%)	651 (12.1%)	613 (11.4%)	685 (12.4%)	805 (13.9%)	1020 (16.5%)
Age	53.0 ± 8.2	52.9 ± 8.5	54.0 ± 8.8	53.4 ± 8.6	53.7 ± 8.6	54.5 ± 8.7	53.6 ± 8.9	54.3 ± 8.5	54.1 ± 8.9	54.0 ± 8.9	53.6 ± 8.9	52.8 ± 9.4	53.7 ± 9.7	52.5 ± 10.2	0.1
Female	124 (22.4%)	126 (21.1%)	125 (19.9%)	134 (19.5%)	156 (22.4%)	133 (20.2%)	127 (22.0%)	146 (24.0%)	164 (26.5%)	170 (26.1%)	153 (25.0%)	172 (25.1%)	200 (24.8%)	280 (27.5%)	0.001
Race															0.03
Black	15 (2.7%)	16 (2.7%)	23 (3.7%)	24 (3.5%)	32 (4.6%)	19 (2.9%)	21 (3.6%)	22 (3.6%)	18 (2.9%)	37 (5.7%)	23 (3.8%)	35 (5.1%)	38 (4.7%)	48 (4.7%)
Hispanic	71 (12.8%)	76 (12.7%)	76 (12.1%)	77 (11.2%)	98 (14.1%)	98 (14.8%)	95 (16.4%)	79 (13.0%)	85 (13.7%)	88 (13.5%)	93 (15.2%)	96 (14.0%)	103 (12.8%)	150 (14.7%)
Other	6 (1.1%)	12 (2.0%)	13 (2.1%)	12 (1.7%)	9 (1.3%)	12 (1.8%)	16 (2.8%)	9 (1.5%)	20 (3.2%)	16 (2.5%)	13 (2.1%)	18 (2.6%)	17 (2.1%)	38 (3.7%)
White	461 (83.4%)	493 (82.6%)	516 (82.2%)	575 (83.6%)	556 (80.0%)	531 (80.5%)	446 (77.2%)	498 (81.9%)	496 (80.1%)	510 (78.3%)	484 (79.0%)	536 (78.2%)	647 (80.4%)	784 (76.9%)
BMI	27.7 ± 5.3	27.8 ± 5.2	27.7 ± 5.5	27.9 ± 5.4	27.7 ± 5.4	28.4 ± 5.5	27.9 ± 5.4	27.9 ± 5.4	28.0 ± 5.6	27.9 ± 5.5	28.1 ± 5.4	28.0 ± 5.3	27.8 ± 5.4	28.0 ± 5.5	0.3
Diabetes															< 0.001
None	433 (78.3%)	458 (76.7%)	493 (78.5%)	538 (78.2%)	548 (78.8%)	484 (73.3%)	440 (76.1%)	485 (79.8%)	487 (78.7%)	518 (79.6%)	509 (83.0%)	560 (81.8%)	659 (81.9%)	828 (81.2%)
Any	103 (18.6%)	122 (20.4%)	116 (18.5%)	138 (20.1%)	134 (19.3%)	167 (25.3%)	131 (22.7%)	109 (17.9%)	127 (20.5%)	128 (19.7%)	100 (16.3%)	122 (17.8%)	144 (17.9%)	187 (18.3%)
Unknown	17 (3.1%)	17 (2.8%)	19 (3.0%)	12 (1.7%)	13 (1.9%)	9 (1.4%)	7 (1.2%)	14 (2.3%)	5 (0.8%)	5 (0.8%)	4 (0.7%)	3 (0.4%)	2 (0.2%)	5 (0.5%)
MELD	20.6 ± 8.4	21.6 ± 9.2	22.6 ± 9.5	22.6 ± 8.7	22.8 ± 8.5	23.9 ± 8.9	24.8 ± 9.0	25.1 ± 8.7	25.8 ± 9.4	26.1 ± 9.5	27.0 ± 9.3	27.5 ± 9.7	28.1 ± 9.6	28.9 ± 10.4	< 0.001
HCC in explant	58 (10.5%)	41 (6.9%)	51 (8.1%)	37 (5.4%)	44 (6.3%)	39 (5.9%)	30 (5.2%)	23 (3.8%)	18 (2.9%)	27 (4.1%)	24 (3.9%)	28 (4.1%)	23 (2.9%)	39 (3.8%)	< 0.001

BMI: Body mass index; HCC: Hepatocellular carcinoma.