Occult hepatitis B virus infection and surgical outcomes in non-B, non-C patients with curative resection for hepatocellular carcinoma

Table 5 Uni- and multi-variate analyses for disease-specific survival after hepatic resection

Characteristic	n	Univariate analysis		Multivariate analysis
		HR (95%CI)	P-value	HR (95%CI)	P-value
Age			0.4181		0.2941
≤ 69	39	1		1
> 69	39	0.74 (0.34-1.54)		0.65 (0.27-1.44)
Gender			0.3814		0.4598
Female	17	1		1
Male	61	1.51 (0.62-4.48)		1.45 (0.56-4.56)
Occult HBV infection			0.4661		0.4693
Absent	51	1		1
Present	27	1.32 (0.60-2.78)		1.33 (0.60-2.88)
Alcohol abuse			0.5064
Absent	59	1
Present	19	1.34 (0.52-3.02)
Diabetes mellitus			0.4775
Absent	51	1
Present	27	1.31 (0.60-2.76)
NASH			0.6755
Absent	70	1
Present	8	1.26 (0.37-3.27)
Obesity			0.6466
Absent	54	1
Present	24	1.20 (0.53-2.53)
Fibrosis			0.1392		0.2147
F0-2	44	1		1
F3,4	34	1.74 (0.84-3.73)		1.62 (0.75-3.58)
Vp			0.0806		0.1478
Absent	47	1		1
Present	31	1.92 (0.91-4.03)		2.00 (0.78-5.08)
T12/T34			0.0824		0.6238
T12	38	1		1
T34	40	1.92 (0.92-4.15)		0.72 (0.19-2.75)
Solitary/multiple			0.0173		0.0984
Solitary	47	1		1
Multiple	31	2.44 (1.17-5.19)		2.55 (0.84-7.96)

HR: Hazard ratio; CI: Confidence interval; Vp: Portal vein invasion; NASH: Non-alcoholic steatohepatitis; HBV: Hepatitis B virus.