Influence of proton pump inhibitors in the development of spontaneous bacterial peritonitis

Table 2 Relationship between selected variables and presence of spontaneous bacterial peritonitis

Variable	n	Events n (%)	Bivariate analysis		Multivariate analysis
			HR (95%CI)	P	HR (95%CI)	P
PPI use
Yes	151	34 (22.5)	1.44 (0.85-2.47)	0.176	1.50 (0.87-2.58)	0.142
No	107	23 (21.5)	1		1
CTP
A	103	15 (26.3)	1		1
B	119	30 (52.6)	2.10 (1.12-3.92)	0.020	2.16 (1.14-4.09)	0.018
C	36	12 (21.1)	3.62 (1.69-7.78)	0.001	3.77 (1.66-8.59)	0.002
MELD
≥ 15	78	19 (33.3)	1.41 (0.81-2.45)	0.226	0.95 (0.52-1.72)	0.854
< 15	180	38 (66.7)	1		1
UGB
Yes	53	11 (19.3)	0.92 (0.48-1.79)	0.808	0.99 (0.51-1.92)	0.967
No	205	46 (83.7)	1

PPI: Proton pump inhibitor; CTP: Child-Turcotte-Pugh; MELD: Model for end-stage liver disease; UGB: Upper gastrointestinal bleeding.