Influence of proton pump inhibitors in the development of spontaneous bacterial peritonitis

Table 1 Sociodemographic and clinical characteristics of patients classified according to the use or not of proton pump inhibitors

Characteristic	Use of PPI		P
	Yes (n = 151)	No (n = 107)
Age (yr)	54.7 ± 11.2	53.1 ± 11.3	0.261
Male sex (%)	63.30%	62.60%	> 0.992
Etiology of liver disease (%)			0.532
Hepatitis C virus	34.50%	34.00%
Alcohol	27.00%	34.90%
Alcohol + hepatitis C virus	24.30%	19.80%
Other	14.20%	11.30%
Platelet count, × 103/mm3	126 ± 81	112 ± 56	0.131
Creatinine, mg/dL	1.07 ± 0.69	0.97 ± 0.27	0.151
Albumin, g/dL	3.4 ± 0.6	3.3 ± 0.6	0.701
Total bilirubin, mg/dL	1.30 (0.80-2.60)	1.40 (0.90-2.60)	0.593
Prothrombin time, INR	1.34 ± 0.29	1.41 ± 0.26	0.241
Child-Turcotte-Pugh score (%)			0.372
A	42.40%	36.40%
B	42.40%	51.40%
C	15.20%	12.10%
MELD score	12.5 ± 3.9	12.7 ± 3.8	0.711
Upper gastrointestinal bleeding (%)	21.90%	18.70%	0.642

Data expressed as mean ± SD, median (25-75 interquartile range) or n (%).

¹Student’s t test;

²Fisher’s exact test;

³Mann-Whitney’s U test. MELD: Model for end-stage liver disease.