Editorial
Copyright ©The Author(s) 2017.
World J Hepatol. Jan 28, 2017; 9(3): 119-125
Published online Jan 28, 2017. doi: 10.4254/wjh.v9.i3.119
Table 1 Main characteristics of studies on dietary factors and hepatocellular carcinoma risk
ConclusionsStudy detailsLocationRef.
Inverse association of vegetable and fruit intake with HCC and upper digestive cancers riskStudy design: Case-control Cases: 285 Controls: 6147 Duration: 1983-1990 Intake: Vegetables and fruitItalyNegri et al[14], 1991
No association between meat and vegetable intake and HCC riskStudy design: Case-control Cases: 97 Controls: 128 Duration: 1995-1998 Intake: Total meat, fruit and vegetablesGreeceKuper et al[44], 2000
Association of red meat intake and HCC risk NAT2 gene polymorphisms play a role in the effect of meat in HCC developmentStudy design: Case-control Cases: 185 Controls: 185 Duration: 1999-2001 Intake: Red and white meat, vegetables and fruitsChinaHuang et al[23], 2003
Inverse association of white meat, coffee and vegetables with HCC mortality Association of egg intake with HCC mortalityStudy design: Cohort Cases: 401 Controls: 110688 Duration: 1988-1999 Intake: Fish, red meat, processed meat, chicken, vegetablesJapanKurozawa et al[17], 2004
Inverse association of white meat, milk, yogurt, eggs, and fruits with HCC riskStudy design: Population based case-control Cases: 185 Controls: 412 Duration: 1999-2002 Intake: Milk, yogurt, white meats, eggs, fruits, vegetablesItalyTalamini et al[10], 2006
Association of red and processed meat intake with HCC riskStudy design: Case-control Cases: 403 Controls: 567169 Duration: 1995-2006 Type of meat: Processed meatUnited StatesCross et al[25], 2007
Association of dietary iron intake and HCC risk Inverse association of linoleic acid (white meat) intake and HCC riskStudy design: Case-control Cases: 185 Controls: 412 Duration: 1999-2002 Intake: Total meatItalyPolesel et al[27], 2007
Association of red meat and saturated fat intake with CLD and HCC risk Inverse association of white meat with HCC and CLD riskStudy design: Case-control Cases: 338 Controls: 495006 Duration: 1995-2006 Intake: White and red meatUnited StatesFreedman et al[4], 2010
Inverse association of fish or n-3 PUFAs intake and HCC riskStudy design: Cohort Cases: 398 Controls: 90296 Duration: 1990-2008 Intake: FishJapanSawada et al[9], 2012
Inverse association of vegetables intake and HCC riskStudy design: Case control Cases: 267 Controls: 132837 Duration: 1997-2006 Intake: MeatChinaZhang et al[41], 2013
Inverse association of fish intake and HCC risk HCC risk decreases by 16% for 20 g/d substitution of fish with meatStudy design: Cohort Cases: 157 Controls: 35628 Duration: 1992-2000 Intake: Dietary flavonoidsWorld-wideZamora-Ros et al[46], 2013
Inverse association of fish intake and HCC risk No association of meat and poultry intake and HCC developmentStudy design: Cohort Cases: 191 Controls: 477206 Duration: 1992-2010 Intake: Total meat, fish, red and white meatEuropeFedirko et al[7], 2013
HCC risk decreases by 8% for every 100 g/d increase in vegetable intakeStudy design: Meta-analysis Cases: 3912 Controls: 1290045 Duration: 1956-2014 Intake: Vegetables and fruitsWorld-wideYang et al[43], 2014