Conjugated hyperbilirubinemia presenting in first fourteen days in term neonates

Table 2 Comparison of causes between early-onset conjugated hyperbilirubinemia and "late-onset" conjugated hyperbilirubinemia groups n (%)

Etiology	ECHB (n = 65)	LCHB (n = 52)	Total (n = 117)	P value
Non-surgical causes	56 (86.2)	45 (86.5)	101 (86.3)	0.962
Multifactorial liver injury	39 (60.0)	18 (34.6)	57 (48.7)	0.007
Sepsis	9 (13.8)	3 (5.8)	12 (10.3)	0.154
Inborn errors of metabolism	3 (4.6)	1 (1.9)	4 (3.4)	0.428
CMV infection	0 (0)	2 (3.8)	2 (1.7)	0.112
Idiopathic	5 (7.7)	21 (40.4)	26 (22.2)	< 0.001
Surgical causes	9 (13.8)	7 (13.5)	16 (13.7)	0.952
Biliary Atresia	8 (12.3)	5 (9.6)	13 (11.1)	0.647
Choledochal cyst	1 (1.5)	2 (3.8)	3 (2.6)	0.435
Non-hepatic causes	48 (73.8)	23 (44.2)	71 (61)	0.001

ECHB: Early-onset conjugated hyperbilirubinemia; LCHB: “Late-onset” conjugated hyperbilirubinemia; CMV: Cytomegalovirus.