Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities

Table 4 Comparison of clinical data within the ethnicities

Characteristics	Controls			Patients
	ASI controls (n = 138) (mean ± SD)	NEI controls (n = 109) (mean ± SD)	P value1	ASI patients (n = 93) (mean ± SD)	NEI patients (n = 163) (mean ± SD)	P value
Age (yr)	34.2 ± 11.9	38.5 ± 12.7	0.006	35.3 ± 8.0	36.5 ± 9.2	0.29
Gender male/female (n)	95/43	72/37	-	87/6	150/13	-
Waist circumference (cm)	83.3 ± 9.4	81.1 ± 10.7	0.27	94.7 ± 10.2	93.8 ± 10.1	0.54
Hip circumference (cm)	93.0 ± 7.1	91.2 ± 6.9	0.23	100.5 ± 8.6	95.1 ± 8.5	0.01
Waist/hip ratio	0.89 ± 0.06	0.89 ± 0.07	1.0	0.95 ± 0.13	0.99 ± 0.12	0.03
BMI (kg/m2)	23.2 ± 4.0	22.1 ± 3.5	0.02	27.7 ± 4.1	25.7 ± 4.0	0.003
ALT (IU/L)	19.8 ± 7.6	24.6 ± 7.9	0.01	88.1 ± 49.5	119.3 ± 68.3	0.01
AST (IU/L)	21.2 ± 5.4	24.6 ± 6.9	0.01	55.3 ± 25.6	72.3 ± 39.8	0.01
Triglycerides (mg/dL)	134.8 ± 72.6	131.4 ± 60.8	0.79	169.7 ± 82.1	180.3 ± 93.7	0.44
HDL (mg/dL)	38.7 ± 8.5	47.9 ± 28.7	0.02	36.3 ± 6.9	40.5 ± 13.8	0.01

¹Unpaired students t test (two tailed). ASI: Ancestral South Indians; NEI: North-East Indians; BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HDL: High density lipoprotein.