Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities

Table 2 Genotype distribution of Tm6SF2 and PNPLA3 variants in the two ethnicities studies

	Ancestral South Indians						North-East Indians
	TM6SF2 rs58542926						TM6SF2 rs58542926
	Controls (n)	Patients (n)	Odds	95%CI	χ2	P value1	Controls (n)	Patients (n)	Odds	95%CI	χ2	P value1
Wild (CC)	110	61	2.7	1.37-5.3	15.28	0.0004	80	110	1.51	0.86-2.66	2.29	0.31
Heterozygous (CT)	18	22					22	44
Homozygous (TT)	0	7					2	6
PNPLA3 rs2281135
Wild (GG)	79	49	1.34	0.78-2.33	2.12	0.34	63	71	1.9	1.5-3.14	6.48	0.03
Heterozygous (GA)	45	35					32	71
Homozygous (AA)	4	6					9	17

¹χ² test. Odds: Odds ratio.