Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities

Table 1 General characteristics of the study

Characteristics	Ancestral South Indians			North-East Indians
	Controls	Patients	P value1	Controls	Patients	P value1
	(n = 138) (mean ± SD)	(n = 93) (mean ± SD)		(n = 109) (mean ± SD)	(n = 163) (mean ± SD)
Age (yr)	34.2 ± 11.9	35.3 ± 8.0	0.43	38.5 ± 12.7	36.5 ± 9.2	0.13
Gender male/female (n)	95/43	87/6	0.64	72/37	150/13	0.84
Waist circumference (cm)	83.3 ± 9.4	94.7 ± 10.2	0.01	81.1 ± 10.7	93.8 ± 10.1	0.01
Hip circumference (cm)	93.0 ± 7.1	100.5 ± 8.6	0.01	91.2 ± 6.9	95.1 ± 8.5	0.01
Waist/hip ratio	0.89 ± 0.06	0.95 ± 0.13	0.01	0.89 ± 0.07	0.99 ± 0.12	0.01
BMI (kg/m2)	23.2 ± 4.0	27.7 ± 4.1	0.01	22.1 ± 3.5	25.7 ± 4.0	0.01
ALT (IU/L)	19.8 ± 7.6	88.1 ± 49.5	0.01	24.6 ± 7.9	119.3 ± 68.3	0.01
AST (IU/L)	21.2 ± 5.4	55.3 ± 25.6	0.01	24.6 ± 6.9	72.3 ± 39.8	0.01
Triglycerides (mg/dL)	134.8 ± 72.6	169.7 ± 82.1	0.01	131.4 ± 60.8	180.3 ± 93.7	0.05
HDL (mg/dL)	38.7 ± 8.5	36.3 ± 6.9	0.09	47.9 ± 28.7	40.5 ± 13.8	0.02

¹Unpaired students t test (two tailed). BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HDL: High density lipoprotein.