Diffusion weighted magnetic resonance imaging of liver: Principles, clinical applications and recent updates

Table 1 Comparison of SSEPI diffusion-weighted magnetic resonance imaging vs conventional magnetic resonance sequences for detection of hepatic metastases[15,20-22,27]

Ref.	b value(s/mm2)	Compared with (Seq)	Sensitivity of DWI vs other sequences	Accuracy of DWI vs other sequences	Advantages of DWI
Bruegel et al[27]	50, 300, 600	5 different T2-TSE (Turbo Spin Echo) sequences	0.88-0.91 compared to 0.45-0.62	0.91-0.92 compared to 0.47-0.67	Better sensitivity and accuracy
Zech et al[21]	50	Fat suppressed T2WI	83% vs 61%	-	Better image quality
					Fewer artifacts
					Better sensitivity
Hardie et al[15]	0, 50, 500	Gadolinium enhanced T1WI	66.3% vs 73.5%	88.2% and 88.2% for DW-MRI, 90.2% and 92.2% for CE MRI, respectively, for observers 1 and 2	Not significantly different
Donati et al[20]	0, 150, 500	Combined (Gd-EOB-DTPA) enhanced MRI/DWI vs Gd-EOB-DTPA enhanced MRI and DWI alone	-	Gd- EOB-DTPA/DWI: 0.84 and 0.83 vs 0.73 and 0.72 for DWI alone	Increase in diagnostic confidence
					No significant increase in diagnostic accuracy
Colagranade et al[22]	0-500	Added value of DWI for lesion detection in unenhanced and Gd-EOB-DTPA enhanced MRI	-62.5% for unenhanced MRI w/o DWI	-81.1% for unenhanced MRI w/o DWI	DWI improved all statistical parameters in the unenhanced examinations, as for nodules either smaller or greater than 1 cm. In EOB-enhanced examinations DWI increased specificity/negative predictive value
			-85.0% for unenhanced MRI+ DWI	-89% for unenhanced MRI + DWI
			-95.6% for CE MRI	-92.9% for CEMRI
			-97.3% for CE MRI + DWI	-95.5% for CE MRI + DWI

DWI: Diffusion-weighted imaging; MRI: Magnetic resonance imaging.