Hepatitis B in patients with hematological diseases: An update

Table 3 Risk of hepatitis B virus reactivation according to different immunosuppressive drug classes (adapted from[21])

Risk	Drug class
High (> 10%)	B-cell depleting agents
	Anthracycline
	Corticosteroids high dose
Moderate (1%-10%)	TNFα inhibitors
	Cytokine and integrin inhibitors
	Tyrosine kinase inhibitors
	Corticosteroids moderate dose
Low (< 1%)	Corticosteroids low dose
	Traditional immunosuppression (e.g., azathioprine or methotrexate)