Serum cholinesterase: A predictive biomarker of hepatic reserves in chronic hepatitis D

Table 4 Optimal cholinesterase cutoffs

State variable	Cholinesterase cut off value (IU/L)	Sensitivity, % (95%CI)	Specificity, % (95%CI)	Likelihood ratio
Ascites	< 3812	80.00 (66.28- 89.97)	81.97 (75.62-87.25)	4.436
CTP ≥ 7	< 3812	79.10 (67.43-88.08)	67.47 (59.78-74.53)	2.432
CTP ≥ 10	< 2853	100.00 (79.41-100.00)	84.79 (79.31-89.29)	6.576
MELD ≥ 10	< 4719	72.09 (61.38-81.23)	80.27 (72.91-86.37)	3.654
MELD ≥ 15	< 2829	91.67 (73.00-98.97)	87.56 (82.31-91.71)	7.369
BEA ≥ 5	< 4719	82.54 (70.90-90.95)	77.06 (70.00-83.15)	3.598
APRI ≥ 1.5	< 3954	58.00 (47.71-67.80)	55.64 (46.78-64.25)	1.307

CTP: Child Turcotte Pugh; MELD: Model for End Stage Liver Disease; APRI: AST to platelet ratio index; BEA: Baseline-event-anticipation.