Is hepatic steatosis associated with left ventricular mass index increase in the general population?

doi:10.4254/wjh.v9.i19.857

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 8, 2017; 9(19): 857-866
Published online Jul 8, 2017. doi: 10.4254/wjh.v9.i19.857

Table 1 General and echocardiographic characteristics of the study population with and without hepatic steatosis at baseline n (%)

	No/one criterion for hepatic steatosis	US⁺ and ALT⁺	P-value
	n = 1106	n = 192
Age (yr), M (SD)	59.6 (8.8)	57.2 (7.8)	P < 0.01
Male gender	442 (40.0)	139 (72.4)	P < 0.001
School education			n.s.
< 10 yr	570 (51.5)	102 (53.1)
10 yr	358 (32.4)	67 (34.9)
> 10 yr	178 (16.1)	23 (12.0)
Waist circumference (cm), M (SD)	89.0 (11.5)	100.8 (10.9)	P < 0.001
Body weight (kg), M (SD)	75.6 (12.8)	88.6 (13.9)	P < 0.001
BMI, (kg/m²), M (SD)	27.4 (4.3)	30.5 (4.6)	P < 0.001
Smoking			P < 0.001
Never-smoker	516 (46.6)	57 (29.7)
Ex-smoker	382 (34.5)	99 (51.7)
Current smoker	208 (18.8)	36 (18.8)
Alcohol consumption (g/d), M (SD)	9.1 (14.5)	15.6 (19.5)	P < 0.001
Diabetes mellitus	100 (9.0)	26 (13.5)	P < 0.001
Systolic blood pressure (mmHg), M (SD)	139.3 (20.2)	148.5 (17.4)	P < 0.001
Diastolic blood pressure (mmHg), M (SD)	84.7 (10.8)	89.9 (10.4)	P < 0.001
Pulse pressure (mmHg), M (SD)	54.6 (14.7)	58.6 (13.4)	P < 0.01
Hypertension	660 (59.7)	163 (84.9)	P < 0.001
Intake of drugs with ATC07	239 (21.6)	39 (20.3)	n.s.
Intake of drugs with ATC08	140 (12.7)	28 (14.6)	n.s.
Intake of drugs with ATC09	198 (17.9)	58 (30.2)	P < 0.001
IVS, M (SD)	9.7 (2.2)	10.9 (2.5)	P < 0.001
LVEDD, M (SD)	50.9 (5.6)	52.4 (5.9)	P < 0.01
PWD, M (SD)	9.6 (1.9)	10.4 (2.0)	P < 0.001
LVM (g), M (SD)	181.8 (53.5)	215.8 (61.3)	P < 0.001
LVMI (g/m^2.7), M (SD)	46.2 (13.3)	51.0 (13.7)	P < 0.001
LVH	499 (45.1)	114 (59.4)	P < 0.001

Pearson χ² and ANOVAs were used for bivariate comparisons. Data are given as numbers and percentages or means (standard deviation). US: Ultrasound; ALT: Alanine aminotransferase; ATC: Anatomical-therapeutic code; IVS: Interventricular septum thickness; LVEDD: Left ventricular end-diastolic diameter; PWD: Posterior wall thickness; LVMI: Left ventricular mass index; LVH: Left ventricular hypertrophy; n.s.: Non-significant.

Citation: Piontek K, Schmidt CO, Baumeister SE, Lerch MM, Mayerle J, Dörr M, Felix SB, Völzke H. Is hepatic steatosis associated with left ventricular mass index increase in the general population? World J Hepatol 2017; 9(19): 857-866
URL: https://www.wjgnet.com/1948-5182/full/v9/i19/857.htm
DOI: https://dx.doi.org/10.4254/wjh.v9.i19.857