Systemic treatment of hepatocellular carcinoma: Past, present and future

doi:10.4254/wjh.v9.i18.797

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jun 28, 2017; 9(18): 797-807
Published online Jun 28, 2017. doi: 10.4254/wjh.v9.i18.797

Table 4 Clinical trials with immunotherapy in hepatocellular carcinoma

Authors	n	Phase	Treatment	Primary end-point
Keynote-224	100	II	Pembrolizumab	RR
ongoing		II	Pembrolizumab	DCR
CheckMate-040		I/II	Nivolumab	Safety
CheckMate-459	726	III	Nivolumab vs Sorafenib	OS
			Nivolumab vs Sorafenib	TTP

RR: Response rate; DCR: Disease control rate; OS: Overall survival; TTP: Time to progression.

Citation: Cidon EU. Systemic treatment of hepatocellular carcinoma: Past, present and future. World J Hepatol 2017; 9(18): 797-807
URL: https://www.wjgnet.com/1948-5182/full/v9/i18/797.htm
DOI: https://dx.doi.org/10.4254/wjh.v9.i18.797