Angiotensin II or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats

Figure 3 Portal pressure induced by angiotensin II or epinephrine. Livers were perfused with Krebs-Henseleit-bicarbonate buffer and after 20 min stabilization, 2 nmol AngII (A, B) or 40 nmol epinephrine (C, D) was injected in bolus into afferent cannula and this moment was considered as time 0 min. The portal pressure was continuously monitored by water manometer attached to the circuit before the cannula. Student’s t-test; ^bP < 0.0001 compared with respective controls for each time point. WIS: Similar to normal rats; SHR: Spontaneously hypertensive rat; WKY: Wistar Kyoto; Ang: Angiotensin; Epi: Epinephrine.