Angiotensin II or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats

Figure 2 Glucose release induced by angiotensin II and epinephrine. Livers were perfused with Krebs-Henseleit-bicarbonate buffer and after stabilization 2 nmol AngII (A, B) or 40 nmol Epi (C, D) was injected in bolus into afferent cannula and this moment was considered as time 0 min. Glucose release was determined in perfusate aliquots collected during all experiments. Student’s t-test; ^aP < 0.05 and ^bP < 0.0001 compared with respective controls for each time point. WIS: Similar to normal rats; SHR: Spontaneously hypertensive rat; WKY: Wistar Kyoto; Ang: Angiotensin; Epi: Epinephrine.