Angiotensin II or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats

Table 3 Portal hypertensive response to angiotensinII or epinephrine

	Portal hypertensive response cmH2O.min
Group	Angiotensin II	n	Epinephrine	n
WIS	26.4 ± 3.2	7	8.2 ± 0.8	10
L-NAME	38.1 ± 4.8	7	18.5 ± 1.9b	8
WKY	29.0 ± 1.1	7	10.0 ± 1.1	8
SHR	25.9 ± 3.7	10	10.5 ± 1.1	6

The portal hypertensive response (PHR; area under the curve) was calculated from portal pressure increase curve vs time after agonist injection and expressed as cmH₂O.min. Student’s t-test;

^bP < 0.0001 compared with respective control (L-NAME vs WIS and SHR vs WKY). WIS: Similar to normal rats; SHR: Spontaneously hypertensive rat; WKY: Wistar Kyoto.