Non-alcoholic fatty liver disease: An expanded review

Table 4 Histologic comparison of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and alcoholic liver disease[129]

Characteristic	NAFLD and NASH	Alcoholic liver disease
Disease severity	Mild	Varying
Mallory-Denk body	Poorly formed	Well formed
Glycogenated nuclei	Common	Less common
Ductular proliferation	Less prominent	More prominent
Fibrosis/cirrhosis	Less common	More common
Sclerosing hyaline necrosis	None/rare	Present
Phlebosclerosis	None/rare	Present
Canalicular cholestasis	None/rare	Present
Foamy degeneration	None/rare	Present

NASH: Non-alcoholic steatohepatitis; NAFLD: Non-alcoholic fatty liver disease.