Cardiovascular assessment in liver transplant for non-alcoholic steatohepatitis patients: What we do, what we should do

Table 1 Methods to detect subclinical atherosclerosis[8]

Carotid ultrasound	CIMT	> 0.9 mm
CT coronary angiography	No. of calcifications in coronary arteries	≥ 1
Endothelial function	Flow-mediated vasodilation brachial artery
	Carotid-femoral pulse wave velocity	> 12 m/s
Morpho-structural alteration	Electrocardiogram (left ventricular hypertrophy)	Sokolov-Lyon > 38 mm; cornell > 2444 mm*ms
Renal function	Slight increase in plasmatic creatinine	M: 1.3-1.5 mg/dL
		F: 1.2-1.4 mg/dL
	Low glomerular filtration	Creatinine clearance < 60 mL/min
	Microalbuminuria	30-300 mg/24 h
		Alb/Cr ≥ 22 (M) or ≥ 31 (F) mg/g Cr
Inflammatory biomarkers	TNF, IL-6, C-reactive protein
Thrombogenic biomarkers	PAI-1, fibrinogen, factor VII

CIMT: Carotid intima-media thickness; CT: Computerized tomography; M: Male; F: Female; TNF: Tumor necrosis factor; IL: Interleukin; PAI-1: Plasminogen activator inhibitor type 1.