Prospective Study
Copyright ©The Author(s) 2017.
World J Hepatol. Apr 8, 2017; 9(10): 519-532
Published online Apr 8, 2017. doi: 10.4254/wjh.v9.i10.519
Table 5 Comparison of patients employed before and after orthotopic liver transplantation to patients employed before but not-employed after orthotopic liver transplantation
n = 41Employed before and after OLT (n = 33)Employed before but not employed after OLT (n = 8)P value
Age, median (range, min-max)50 (42, 18-60)54 (30, 29-59)0.13
Sex (male/female)18 (54.5%)/156 (75.0%)/20.43
Profession Academic/non-academic11 (34.4%)/21 (NS 1)3 (37.5%)/51.00
labMELD median (range, min-max)18 (33, 7-40)17 (31, 9-40)0.91
Aetiology of liver disease0.19
PSC122
PBC00
Alcohol30
HCV60
HBV22
AIH21
M. Wilson20
Others63
History of HE (+/-)9 (27.3%)/242 (25.0%)/61.00
Neurological complications (+/-)11 (33.3%)/225 (62.5%)/30.23
PHES after OLT, median (min/max)1 (-4/+2) (n = 25)0 (-7/+4) (n = 7)0.93
CFF after OLT, mean ± SD45.3 ± 3.7 (n = 24)41.7 ± 5.0 (n = 7)0.04
RBANS after OLT Immediate memory, mean ± SD101.6 ± 14.1 (n = 26)89.4 ± 10.0 (n = 7)0.04
RBANS after OLT Visuospatial/constructional median (range, min-max)84 (64, 62-126) (n = 26)89 (57, 64-121) (n = 7)0.68
RBANS after OLT Language, mean ± SD103.2 ± 14.6 (n = 26)95.1 ± 24.2 (n = 7)0.27
RBANS after OLT Attention, mean ± SD100.8 ± 14.1 (n = 26)87.1 ± 18.6 (n = 7)0.04
RBANS after OLT Delayed memory, median (range, min-max)98 (109, 10-119) (n = 26)95 (17, 88-105) (n = 7)0.16
RBANS after OLT Sum score, mean ± SD492.0 ± 47.8 (n = 26)457.0 ± 56.8 (n = 7)0.11
RBANS after OLT Total scale, mean ± SD97.7 ± 13.7 (n = 26)88.3 ± 14.6 (n = 7)0.12
P value ≤ 0.05 is considered significant. NS: Not specified; OLT: Orthotopic liver transplantation; labMELD: Laboratory Model of End Stage Liver Disease; PSC: Primary sclerosing cholangitis; PBC: Primary biliary cirrhosis; HCV: Hepatitis C virus; HBV: Hepatitis B virus; AIH: Autoimmune hepatitis; HE: Hepatic encephalopathy; PHES: Psychometric hepatic encephalopathy score; CFF: Critical flicker frequency; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status.