Copyright
©The Author(s) 2016.
World J Hepatol. Feb 18, 2016; 8(5): 301-306
Published online Feb 18, 2016. doi: 10.4254/wjh.v8.i5.301
Published online Feb 18, 2016. doi: 10.4254/wjh.v8.i5.301
Table 2 Distribution of DNA methylation by hepatocellular carcinoma status
Locus | Gene | HCC cases | Controls | P1 | ||
Mean | SD | Mean | SD | |||
cg00028598 | GABRA5 | 0.92 | 0.04 | 0.92 | 0.07 | 0.81 |
cg00108164 | ACP1 | 0.01 | 0.02 | 0.00 | 0.01 | 0.55 |
cg00249511 | SCT | 0.01 | 0.04 | 0.01 | 0.04 | 0.80 |
cg00753478 | LDHB | 0.09 | 0.08 | 0.08 | 0.06 | 0.12 |
cg00817367 | GRASP | 0.01 | 0.04 | 0.01 | 0.01 | 0.23 |
cg00939495 | DRD5 | 0.22 | 0.10 | 0.22 | 0.12 | 0.95 |
cg01530024 | STK32B | 0.97 | 0.08 | 0.97 | 0.07 | 0.79 |
cg01566592 | RIMS2 | 0.10 | 0.09 | 0.09 | 0.08 | 0.32 |
cg01860297 | BASP1 | 0.96 | 0.03 | 0.95 | 0.08 | 0.49 |
cg02527669 | OBSL1 | 0.02 | 0.02 | 0.03 | 0.05 | 0.53 |
cg02553663 | SECTM1 | 0.03 | 0.04 | 0.03 | 0.03 | 0.65 |
cg02710296 | C1orf14 | 0.33 | 0.11 | 0.33 | 0.11 | 0.92 |
cg02736548 | FAM109B | 0.08 | 0.09 | 0.08 | 0.09 | 0.46 |
cg03306486 | APC2 | 0.02 | 0.02 | 0.01 | 0.02 | 0.44 |
cg03396005 | APCDD1 | 0.92 | 0.04 | 0.92 | 0.06 | 0.99 |
cg03621881 | BRUNOL6 | 0.04 | 0.05 | 0.03 | 0.04 | 0.70 |
cg04920951 | GSTP1 | 0.01 | 0.07 | 0.00 | 0.02 | 0.22 |
cg05328339 | PTPRN2 | 0.89 | 0.09 | 0.88 | 0.10 | 0.55 |
cg05661282 | ZNF154 | 0.03 | 0.05 | 0.03 | 0.08 | 0.75 |
cg05699035 | KCNK2 | 0.86 | 0.07 | 0.86 | 0.08 | 0.99 |
cg05833351 | CUGBP2 | 0.95 | 0.07 | 0.95 | 0.08 | 0.70 |
cg05970721 | HS3ST2 | 0.90 | 0.10 | 0.91 | 0.10 | 0.49 |
cg06382344 | TBR1 | 0.02 | 0.03 | 0.03 | 0.05 | 0.13 |
cg06445348 | ILDR2 | 0.02 | 0.06 | 0.01 | 0.01 | 0.24 |
cg06641285 | TIMP2 | 0.02 | 0.02 | 0.02 | 0.05 | 0.74 |
cg07061738 | SMOC2 | 0.94 | 0.08 | 0.94 | 0.11 | 0.75 |
cg07689503 | MTHFD2 | 0.00 | 0.00 | 0.00 | 0.01 | 0.27 |
cg07759394 | GLB1L2 | 0.01 | 0.03 | 0.01 | 0.02 | 0.44 |
cg07765706 | KCNQ3 | 0.95 | 0.03 | 0.95 | 0.08 | 0.12 |
cg08328777 | DUOX1 | 0.07 | 0.05 | 0.07 | 0.06 | 0.30 |
cg08714590 | FZD1 | 0.86 | 0.12 | 0.86 | 0.12 | 0.43 |
cg08738570 | C1orf70 | 0.09 | 0.10 | 0.09 | 0.08 | 0.69 |
cg09210956 | SNTG2 | 0.67 | 0.09 | 0.67 | 0.12 | 0.93 |
cg09433131 | KCNB2 | 0.94 | 0.06 | 0.93 | 0.10 | 0.43 |
cg09489445 | ZNF788 | 0.01 | 0.03 | 0.01 | 0.04 | 0.92 |
cg09901035 | PLEKHG4B | 0.87 | 0.06 | 0.87 | 0.08 | 0.66 |
cg10272601 | WNK2 | 0.30 | 0.07 | 0.28 | 0.08 | 0.04 |
cg10342963 | IGF1R | 0.81 | 0.13 | 0.79 | 0.15 | 0.07 |
cg11349423 | OPCML | 0.48 | 0.15 | 0.48 | 0.16 | 0.93 |
cg11377136 | PKDREJ | 0.03 | 0.03 | 0.03 | 0.03 | 0.69 |
cg11686528 | ABR | 0.01 | 0.07 | 0.01 | 0.06 | 0.60 |
cg12296772 | MTMR7 | 0.07 | 0.06 | 0.07 | 0.07 | 0.78 |
cg12610564 | SLC39A12 | 0.98 | 0.01 | 0.97 | 0.07 | 0.09 |
cg12680131 | TPO | 0.80 | 0.09 | 0.82 | 0.11 | 0.02 |
cg12852139 | MYO10 | 0.96 | 0.02 | 0.95 | 0.06 | 0.70 |
cg13204512 | RNF135 | 0.01 | 0.06 | 0.01 | 0.02 | 0.23 |
cg13517866 | SMOC2 | 0.89 | 0.11 | 0.89 | 0.10 | 0.58 |
cg13564825 | PPP1R14A | 0.01 | 0.05 | 0.01 | 0.02 | 0.98 |
cg13604246 | ANKMY1 | 0.11 | 0.08 | 0.11 | 0.09 | 0.68 |
cg13611121 | COL5A1 | 0.80 | 0.08 | 0.80 | 0.10 | 0.73 |
cg13782274 | KCNQ2 | 0.94 | 0.08 | 0.93 | 0.11 | 0.39 |
cg13791254 | FOXE1 | 0.02 | 0.02 | 0.01 | 0.03 | 0.62 |
cg13879483 | USP44 | 0.08 | 0.06 | 0.07 | 0.07 | 0.34 |
cg13895235 | PRKAR1B | 0.01 | 0.01 | 0.01 | 0.03 | 0.39 |
cg14183206 | HLA-L | 0.24 | 0.10 | 0.23 | 0.09 | 0.61 |
cg14486338 | KCNS2 | 0.12 | 0.07 | 0.12 | 0.07 | 0.53 |
cg14644001 | PRRT1 | 0.04 | 0.03 | 0.04 | 0.05 | 0.63 |
cg14645545 | SLC11A1 | 0.20 | 0.12 | 0.19 | 0.12 | 0.83 |
cg14715697 | HRNBP3 | 0.70 | 0.08 | 0.71 | 0.08 | 0.20 |
cg14866200 | SHISA3 | 0.02 | 0.07 | 0.02 | 0.06 | 0.74 |
cg14988503 | CDKL2 | 0.02 | 0.03 | 0.02 | 0.03 | 0.85 |
cg15092343 | MSX1 | 0.07 | 0.05 | 0.07 | 0.04 | 0.48 |
cg15167871 | TCERG1L | 0.92 | 0.10 | 0.92 | 0.11 | 0.98 |
cg15549700 | AJAP1 | 0.96 | 0.05 | 0.96 | 0.08 | 0.53 |
cg15760257 | SARM1 | 0.01 | 0.01 | 0.01 | 0.05 | 0.35 |
cg17264670 | RGS17 | 0.08 | 0.06 | 0.08 | 0.08 | 0.94 |
cg17497608 | FZD1 | 0.83 | 0.11 | 0.84 | 0.12 | 0.43 |
cg17725364 | COL6A3 | 0.96 | 0.10 | 0.96 | 0.09 | 0.86 |
cg18537730 | IZUMO1 | 0.16 | 0.07 | 0.16 | 0.08 | 0.63 |
cg19429281 | ZNF702P | 0.02 | 0.01 | 0.02 | 0.03 | 0.40 |
cg19464917 | ISL2 | 0.06 | 0.04 | 0.05 | 0.03 | 0.17 |
cg20129213 | RIMS2 | 0.01 | 0.05 | 0.01 | 0.05 | 0.47 |
cg20399616 | BCAT1 | 0.05 | 0.08 | 0.04 | 0.08 | 0.40 |
cg21385746 | LOC150568 | 0.96 | 0.10 | 0.95 | 0.11 | 0.80 |
cg21472506 | OTX1 | 0.01 | 0.04 | 0.01 | 0.04 | 0.98 |
cg21790626 | ZNF154 | 0.04 | 0.04 | 0.05 | 0.05 | 0.32 |
cg22403469 | RIMBP2 | 0.83 | 0.05 | 0.83 | 0.08 | 0.63 |
cg22511877 | MYT1L | 0.56 | 0.17 | 0.60 | 0.16 | 0.01 |
cg22524061 | OSR2 | 0.23 | 0.09 | 0.22 | 0.09 | 0.48 |
cg22655988 | CRMP1 | 0.96 | 0.08 | 0.96 | 0.10 | 0.77 |
cg22789900 | MIXL1 | 0.00 | 0.01 | 0.01 | 0.04 | 0.55 |
cg23004031 | MGMT | 0.55 | 0.31 | 0.58 | 0.32 | 0.41 |
cg23391785 | DNM3 | 0.02 | 0.06 | 0.01 | 0.04 | 0.28 |
cg23498518 | POM121L12 | 0.79 | 0.07 | 0.80 | 0.10 | 0.36 |
cg23864180 | ADARB2 | 0.90 | 0.06 | 0.91 | 0.07 | 0.26 |
cg24274117 | C20orf195 | 0.03 | 0.07 | 0.04 | 0.07 | 0.52 |
cg24425838 | C2CD4D | 0.05 | 0.08 | 0.05 | 0.07 | 0.98 |
cg24432073 | CDKL2 | 0.02 | 0.03 | 0.02 | 0.04 | 0.84 |
cg24563094 | FAM59B | 0.10 | 0.04 | 0.10 | 0.05 | 0.55 |
cg24602704 | ATP10A | 0.97 | 0.02 | 0.97 | 0.07 | 0.46 |
cg24816460 | CDYL | 0.03 | 0.07 | 0.03 | 0.07 | 0.51 |
cg25480336 | ZFP64 | 0.01 | 0.02 | 0.01 | 0.01 | 0.16 |
cg25577023 | AMN | 0.09 | 0.09 | 0.09 | 0.09 | 0.82 |
cg25622366 | OTX1 | 0.02 | 0.07 | 0.02 | 0.05 | 0.66 |
cg26010734 | EPHX3 | 0.05 | 0.05 | 0.05 | 0.04 | 0.43 |
cg26841013 | WNT3A | 0.03 | 0.02 | 0.03 | 0.03 | 0.45 |
- Citation: Wu HC, Shen J, Yang HI, Tsai WY, Chen CJ, Santella RM. Blood DNA methylation markers in prospectively identified hepatocellular carcinoma cases and controls from Taiwan. World J Hepatol 2016; 8(5): 301-306
- URL: https://www.wjgnet.com/1948-5182/full/v8/i5/301.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i5.301