Lack of hepcidin expression attenuates steatosis and causes fibrosis in the liver

Figure 8 Expression of genes involved in lipogenesis, lipid storage and secretion. The mRNA expression levels of Srebp-1c (A and B), Fsp27 (C and D), and Mttp (E and F) in the livers of floxed and knockout mice fed with regular and high fat sucrose (HFS) diets, was determined by real-time polymerase chain reaction. Gene expression in high fat-fed floxed or knockout and regular diet-fed knockout mice for 3 (A, C and E) or 7 mo (B, D and F) was expressed as fold change of that in floxed mice fed with a regular diet for the same time period.