Fractionation of gamma-glutamyltransferase in patients with nonalcoholic fatty liver disease and alcoholic liver disease

Figure 1 Gamma-glutamyltransferase-specific elution profiles of representative serum samples (two of each) obtained from the control group subjects (A and B), patients with alcoholic liver disease (C and D), and patients with non-alcoholic fatty liver disease (E and F). On the basis of the molecular weight calibration curve (data not shown), these four peaks are equivalent to big-GGT (MW > 2000 kDa, eluted between 6.25-9.50 mL), medium GGT (MW 940 kDa, eluted between 9.5-12.25 mL), small GGT (MW 140 kDa, eluted between 12.25–15.5 mL) and free-GGT (MW 70 kDa, eluted between 15.5-20 mL), respectively. GGT: Gamma-glutamyltransferase.