Prevalence and risk factors of acute-on-chronic liver failure in a single center from Argentina

Table 6 Comparative results between groups with and without acute on chronic liver failure n (%)

	ACLF	No ACLF	P vaule	OR	95%CI
Age (yr ± SD)	60 ± 11	60 ± 11	1.00
Male	23 (79)	44 (62)	0.11	2.3	0.78-7.43
Child Pugh (score ± DS)	10.2 ± 2.1	8.4 ± 1.6	< 0.0001
MELD (score ± DS)	20.7 ± 8.5	12.3 ± 4	< 0.0001
Active alcoholism	9 (31)	22 (31)	1.00	1	0.3-2.8
Prior ascites	18 (62)	29 (41)	0.07	2.3	0.9-6.3
Prior encephalopthy, n (%)	9 (31)	10 (14)	0.08	2.74	0.9-8.7
Esophageal varices	18 (62)	37 (52)	0.38	1.5	0.5-4
Ascites	27 (93)	43 (60.5)	0.001	8.8	1.8-58.1
Variceal hemorrhage	4 (13.7)	10 (14)	1	0.97	0.2-3.8
White cell count (n/mm3± SD)	15.300 ± 10.770	8.033 ± 5.601	< 0.0001
Serum sodium (mEq/L ± SD)	133.3 ± 6.9	135.1 ± 5.3	0.16
CRP (mg/L ± SD)	50.9 ± 46.4	28.6 ± 23.4	0.002
Mortality	18 (62)	4 (5.6)	< 0.0001

OR: Odds ratio; 95%CI: Confidence interval 95%; SD: Standard deviation; CRP: C-reactive protein; ACLF: Acute-on-chronic liver failure.