Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients

Table 5 Accuracy indices of the discriminant score in the prediction of fibrosis

Stage of fibrosis	Cut-off value	AUC	95%CI	Sens	Specific	PPV	NPV	PLR	NLR
Mild fibrosis (F0-F1)	-0.31 or more negative	0.88	0.84-0.91	67.2%	86.3%	83.6%	69.5%	4.9	0.38
Moderate fibrosis (F2)	> -0.31 up to +0.86	0.64	0.61-0.74	53.1%	74.1%	33%	86.8%	2.0	0.63
Advanced fibrosis (F3-F4)	> 0.86	0.91	0.88-0.94	73%	90.9%	74.4%	90.1%	8.0	0.3

Sens: Sensitivity; Specific: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; PLR: Positive likelihood ratio; NLR: Negative likelihood ratio; AUC: Area under the curve.