Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients

Table 1 Presentation of quantitative variable as means, standard deviation, median and quartile range by stages of fibrosis

Variant	Total (n = 332)	F0 (n = 43)	F1 (n = 136)	F2 (n = 64)	F3 (n = 45)	F4 (n = 44)
Age (yr)
Mean ± SD	42 ± 9.8	31.6 ± 7.4	41.1 ± 9.2	42 ± 7.4	48.5 ± 8.9	49.7 ± 7.5
Median ± QR	42 ± 15	31 ± 11	40.5 ± 15	42 ± 10	50 ± 11	49 ± 13
Gender (male)
n (%)	184 (55.4)	24 (55.8)	77 (56.6)	40 (62.5)	22 (48.9)	21 (47.7)
HOMA-IR
Mean ± SD	3.1 ± 1.3	2.4 ± 0.9	2.7 ± 1	3.4 ± 1.2	4.1 ± 1.7	4.0 ± 1.2
Median ± QR	2.9 ± 1.6	2.4 ± 1.8	2.7 ± 1.4	3.4 ± 1.4	4.1 ± 2.5	4.2 ± 2
ACE (U/mL)
Mean ± SD	286.7 ± 132.9	248.9 ± 122.3	277.3 ± 129	287.2 ± 122.5	325.3 ± 173.3	320.4 ± 122.4
Median ± QR	260 ± 180	235 ± 127.5	260 ± 195	300 ± 190	275 ± 171.3	285 ± 138.8
Glucose (mmol)
Mean ± SD	5.1 ± 0.9	5 ± 0.6	5.1 ± 0.9	4.8 ± 0.8	5.3 ± 0.9	5.7 ± 1.1
Median ± QR	5.1 ± 1.22	5.1 ± 1.1	4.9 ± 1.1	4.7 ± 1.2	5.3 ± 1.6	5.4 ± 1.7
ALT (U/L)
Mean ± SD	58.4 ± 36.9	37 ± 16.6	53.6 ± 37.7	55.5 ± 30.4	79.8 ± 42.6	82 ± 33.9
Median ± QR	44 ± 52	36 ± 24.3	43 ± 43	47 ± 53	81.5 ± 57.5	90 ± 41.5
AST (U/L)
Mean ± SD	53.2 ± 37.6	27.5 ± 10.9	41.1 ± 21.3	55 ± 35.4	87.2 ± 53.9	88.6 ± 42.5
Median ± QR	36 ± 43	23.5 ± 18.3	34 ± 25.8	36 ± 39	89 ± 61.3	85 ± 67.3
Platelet (× 109/L)
Mean ± SD	213.6 ± 70	225.8 ± 49.4	240 ± 65.4	207.1 ± 70.2	164.8 ± 73.8	158.3 ± 36.2
Median ± QR	215 ± 105	221.5 ± 77.5	233 ± 82.5	226 ± 120	150.5 ± 90.3	162.5 ± 38.8
BMI
Mean ± SD	27.4 ± 4.5	25.7 ± 4.3	27.9 ± 5.1	27.8 ± 4.3	27.2 ± 3.6	26.6 ± 3.1
Median ± QR	27.7 ± 5.8	25.9 ± 7.5	28.3 ± 7.8	27.7 ± 5.3	27.6 ± 4.6	27.8 ± 4.2
Waist: Hip ratio
Mean ± SD	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1
Median ± QR	0.9 ± 0.1	0.9 ± 0.04	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1
Insulin (uU/mL)
Mean ± SD	13.9 ± 5.3	11.1 ± 4.2	12.2 ± 4.5	15.8 ± 4.9	17.7 ± 7.1	15.7 ± 3.3
Median ± QR	13.6 ± 6.7	12.6 ± 7.2	12.3 ± 6.3	14.6 ± 3.4	16.7 ± 10.2	16.6 ± 5.8
Albumin (g/dL)
Mean ± SD	4.2 ± 0.5	4.2 ± 0.3	4.4 ± 0.5	4 ± 0.8	4 ± 0.5	4 ± 0.3
Median ± QR	4.2 ± 0.6	4.1 ± 0.5	4.4 ± 0.5	4.2 ± 0.8	3.9 ± 0.7	4 ± 0.6
Viral load (IU/mL)
Mean ± SD	372826.7 ± 902784.9	338113.1 ± 624770.4	409890.1 ± 941388.1	283586 ± 858939.26	264338.4 ± 452377.9	119830.8 ± 162200.8
Median ± QR	78000 ± 280088	117466.5 ± 358614	59112 ± 310055	156797 ± 251419	47546 ± 278956	97133 ± 167712

SD: Standard deviation; QR: Quartile range; HOMA-IR: Homeostasis model for insulin resistance, a mathematically calculated formula; ACE: Angiotensin converting enzyme; AST: Aspartate transaminase enzyme; ALT: Alanine amino transferase; BMI: Body mass index.