Copyright
©The Author(s) 2016.
World J Hepatol. Oct 18, 2016; 8(29): 1234-1243
Published online Oct 18, 2016. doi: 10.4254/wjh.v8.i29.1234
Published online Oct 18, 2016. doi: 10.4254/wjh.v8.i29.1234
Smoking habits | Alcoholic habit | |||||||||||||
No smoker | Smoker | 2Pinteraction | Non-alcoholic | Alcoholic | 2Pinteraction | |||||||||
Case | Control | 1OR(95%CI) | Case | Control | OR+(95%CI) | Case | Control | 1OR(95%CI) | Case | Control | 1OR (95%CI) | |||
MTRA2756G | ||||||||||||||
A/A | 50 | 142 | 1.00 | 29 | 121 | 1.00 | 0.39 | 36 | 137 | 1.00 | 43 | 126 | 1.00 | 0.73 |
A/G-G/G | 21 | 57 | 1.35 (0.72-2.53) | 16 | 36 | 2.07 (0.97-4.41) | 17 | 53 | 1.46 (0.72-2.97) | 20 | 40 | 1.74 (0.89-3.38) | ||
MTRRA66G | ||||||||||||||
A/A | 26 | 55 | 1.00 | 11 | 50 | 1.00 | 0.051 | 14 | 53 | 1.00 | 23 | 52 | 1.00 | 0.42 |
A/G-G/G | 45 | 144 | 0.63 (0.35-1.17) | 34 | 107 | 1.71 (0.77-3.82) | 39 | 137 | 1.17 (0.56-2.45) | 40 | 114 | 0.78 (0.42-1.48) | ||
MTHFRC677T | ||||||||||||||
C/C | 31 | 85 | 1.00 | 17 | 64 | 1.00 | 0.96 | 24 | 85 | 1.00 | 24 | 64 | 1.00 | 0.76 |
C/T-T/T | 40 | 114 | 0.96 (0.54-1.71) | 28 | 93 | 0.98 (0.48-2.02) | 29 | 105 | 1.05 (0.54-2.02) | 39 | 102 | 0.91 (0.49-1.69) | ||
MTHFRA1298C | ||||||||||||||
A/A | 33 | 120 | 1.00 | 24 | 85 | 1.00 | 0.32 | 23 | 113 | 1.00 | 34 | 92 | 1.00 | 0.56 |
A/C-C/C | 38 | 79 | 1.68 (0.95-3.00) | 21 | 72 | 1.06 (0.53-2.13) | 30 | 77 | 1.83 (0.95-3.54) | 29 | 74 | 1.11 (0.61-2.03) |
- Citation: Peres NP, Galbiatti-Dias ALS, Castanhole-Nunes MMU, da Silva RF, Pavarino ÉC, Goloni-Bertollo EM, Ruiz-Cintra MT. Polymorphisms of folate metabolism genes in patients with cirrhosis and hepatocellular carcinoma. World J Hepatol 2016; 8(29): 1234-1243
- URL: https://www.wjgnet.com/1948-5182/full/v8/i29/1234.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i29.1234