Potential role of killer immunoglobulin receptor genes among individuals vaccinated against hepatitis B virus in Lebanon

doi:10.4254/wjh.v8.i29.1212

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World Journal of Hepatology

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1948-5182

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World J Hepatol. Oct 18, 2016; 8(29): 1212-1221
Published online Oct 18, 2016. doi: 10.4254/wjh.v8.i29.1212

Table 5 The relationship between AA, AB and BB genotypes and the expression of killer immunoglobulin receptor genes among the study participants n (%)

KIR genes	AA (n = 44)	AB (n = 41)	BB (n = 16)	Test¹	P value
2DL2	0 (0.00)	41 (100.00)	16 (100.00)	101	0.00^a
2DL3	44 (100.00)	41 (100.00)	0 (0.00)	101	0.00^a
2DL5A	10 (22.70)	10 (22.70)	5 (31.25)	FET	0.782
2DL5B	1 (2.27)	20 (24.39)	8 (50.00)	FET	0.00^a
2DS1	16 (36.30)	18 (43.90)	7 (43.75)	0.579	0.749
2DS2	0 (0.00)	40 (97.50)	16 (100.00)	97.051	0.00^a
2DS3	3 (6.80)	30 (73.17)	14 (87.50)	50.38	0.00^a
2DS4*001/002	16 (36.40)	19 (37.50)	6 (37.50)	0.952	0.621
2DS4*003/007	38 (86.40)	31 (75.60)	14 (87.50)	FET	0.392
2DS5	14 (31.80)	16 (39.00)	5 (31.30)	0.584	0.747
3DS1	18 (40.90)	18 (43.90)	6 (40.00)	0.107	0.948
3DP*001/002/004	2 (4.50)	10 (24.40)	5 (31.30)	FET	0.0006^a

¹The statistical test performed to determine the relationship between AA, AB and BB genotypes and the expression of KIR genes among vaccinated and non-vaccinated study participants. FET refers to the Fisher’s exact test and the rest of the values represent the Pearson χ² value.

^aP < 0.05, significant. KIR: Killer immunoglobulin receptor; FET: Fisher-exact test.

Citation: Melhem NM, Mahfouz RA, Kreidieh K, Abdul-Khalik R, El-Khatib R, Talhouk R, Musharrafieh U, Hamadeh G. Potential role of killer immunoglobulin receptor genes among individuals vaccinated against hepatitis B virus in Lebanon. World J Hepatol 2016; 8(29): 1212-1221
URL: https://www.wjgnet.com/1948-5182/full/v8/i29/1212.htm
DOI: https://dx.doi.org/10.4254/wjh.v8.i29.1212