Review
Copyright ©The Author(s) 2016.
World J Hepatol. Oct 8, 2016; 8(28): 1157-1168
Published online Oct 8, 2016. doi: 10.4254/wjh.v8.i28.1157
Figure 1
Figure 1 “Multiple hit hypothesis” accounting for the development of autoimmune disease. Interplay between immunological, genetic, epigenetic and environmental factors is thought to account for the loss of tolerance to self constituents in AILD. AILD: Autoimmune liver disease.