Copyright
©The Author(s) 2016.
World J Hepatol. Oct 8, 2016; 8(28): 1157-1168
Published online Oct 8, 2016. doi: 10.4254/wjh.v8.i28.1157
Published online Oct 8, 2016. doi: 10.4254/wjh.v8.i28.1157
PBC | PSC | AIH | |
Female/male ratio | 10/1 | 1/2 | 4/1 |
Average age at presentation | 50 | 41 | Childhood/adolescence and approximately 40 |
Incidence | 0.33-5.8/100000 | 0-1.3/100000 | 0.08-3/100000 |
Prevalence | 1.91-40.2/100000 | 0-16.2/100000 | 11.6-35.9/100000 |
Risk within family | 1st degree relative incidence 4%-6% | Unknown | Unknown |
Concordance in monozygotic twins | 60% | Only case reports | Only case reports |
Note | AMA positivity | Frequent association with IBD Increased risk of hepatobiliary/colorectal malignancies | Positivity for ANA and or SMA (AIH type-1) or anti-LKM-1 (AIH type-2) |
- Citation: Liberal R, Grant CR. Cirrhosis and autoimmune liver disease: Current understanding. World J Hepatol 2016; 8(28): 1157-1168
- URL: https://www.wjgnet.com/1948-5182/full/v8/i28/1157.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i28.1157