Evidence-Based Medicine
Copyright ©The Author(s) 2016.
World J Hepatol. Sep 8, 2016; 8(25): 1075-1086
Published online Sep 8, 2016. doi: 10.4254/wjh.v8.i25.1075
Table 3 Levels of recommendation according to the available evidence
RecommendationDescription
AThe consensus strongly recommends the mentioned intervention or service. This recommendation is based on high quality evidence, with a benefit that significantly exceeds the risks
BThe consensus recommends the regular clinical use of the mentioned intervention or service. This recommendation is based on moderate quality evidence, with a benefit that exceeds the risks
CThe consensus does not make any positive or negative recommendation regarding the mentioned intervention or service. A categorical recommendation is not provided, because the evidence (of at least moderate quality) does not show a satisfactory risk/benefit relationship. The decision has to be made on a case-by-case basis
DThe consensus makes a negative recommendation against the mentioned intervention or service. The recommendation is based on at least moderate quality evidence, not showing any benefit or where the risk or damage exceeds the benefits of the intervention
IThe consensus concludes that the evidence is insufficient, due to low-quality studies, heterogeneous results or because the risk/benefit balance cannot be determined