Liver resections can be performed safely without Pringle maneuver: A prospective study

Table 5 Pre-, intra- and postoperative values of Indocyangreen-clearance testing were available in 45 liver surgeries and were presented as total as well as subgroups according to the type of liver resection

ICG data1	Total (n = 45)	Anatomical resections (n = 27)	Atypical resections > 5 cm (n = 13)	Combination of anatomical and atypical resections > 5 cm (n = 5)	P-values
R15 (%, norm 0-10)
Preoperative	3.6 (0.1 to 28.4)	3.6 (0.1 to 28.4)	3.6 (0.2 to 16.3)	2.7 (0.8 to 15)	0.4573
Intraop. after resection	12.4 (0.5 to 69.8)	17.3 (0.5 to 69.8)	6.5 (0.9 to 15.3)	22.4 (1.3 to 28.8)	0.03023
Postoperative day 2	5.8 (0.2 to 26.7)	7.8 (0.2 to 26.7)	3.2 (0.7 to 13.4)	7.6 (0.9 to 12.1)	0.04203
R15 Δ2	1.8 (-8.4 to 14.1)	4.2 (-8.4 to 14.1)	-0.2 (-5.2 to 9.8)	0.5 (-0.9 to 8.4)	0.0693
PDR (%, norm 18-25)
Preoperative	22.2 (8.4 to 48)	21.4 (8.4 to 48)	22.2 (12.1 to 40.1)	24.1 (12.0 to 31.0)	0.6772
Intraop. after resection	14.4 (2.4 to 35.3)	11.7 (2.4 to 35.3)	18.2 (12.5 to 31.2)	9.5 (8.3 to 26.0)	0.00473
Postoperative day 2	19.0 (8.8 to 40.3)	17.5 (8.8 to 40.3)	22.5 (13.4 to 28.4)	17.5 (14.1 to 31.3)	0.5732
PDR Δ2	-1.4 (-15 to 37.1)	-3.7 (-12.9 to 37.1)	0.1 (-15 to 7.4)	-2.2 (-24.6 to 4.7)	0.5534

¹Median values and range of data are presented. As sensitive indicator for liver function the retention rate after 15 min (R15) and the plasma disappearance rate (PDR) were evaluated;

²Δ values of R15 and PDR were determined by the difference of preoperative and postoperative day 2 values. P values were calculated, comparing the variable of interest in between the different resection group (one-way Anova analysis of variance);

³Denote statistical significance among resections in the group of anatomical, atypical, and combinated resections. ICG: Indocyanine green clearance.