Liver resections can be performed safely without Pringle maneuver: A prospective study

Table 4 Perioperative alterations of laboratory parameters, shown as total and as subgroups according to the types of resection

Serum parameters	Total (n = 143)	Anatomical resections (n = 77)	Atypical resections > 5 cm (n = 50)	Combination of ana-tomical and atypical resections > 5 cm (n = 16)	P-values
	Median Δ-values1 (ranges)	Median Δ-values1 (ranges)	Median Δ-values1 (ranges)	Median Δ-values1 (ranges)
ASAT (U/L, norm < 41)	304 (-486 to 9885)	346 (-486 to 9885)	285 (-137 to 2361)	463 (-5 to 1270)	0.1747
ALAT (U/L, norm < 41)	299 (-356 to 3909)	300 (-356 to 3909)	245 (-250 to 2200)	421 (-27 to 1093)	0.2635
Bilirubin (μmol/L, norm < 20)	7 (-130 to 234)	9 (-130 to 234)	4 (-36 to 152)	7 (-0.1 to 33.4)	0.4605
Ammonia (μmol/L, norm 12-48)	393 (14 to 155)	413 (14 to 155)	393 (20 to 90)	373 (25 to152)	0.50264
Albumin (g/L, norm 35-50)	-8 (-41 to 192)	-8 (-19 to 12)	-6 (-20 to 192)	-8 (-18 to 1)	0.2262
Hemoglobin (g/L, norm 130-180)	-37 (-83 to 0)	-35 (-83 to 0)	-37 (-71 to -4)	-39 (-68 to -22)	0.4654
Prothrobine time: Quick (%, norm > 70)	-27 (-108 to 62)	-32 (-81 to -9)	-22 (-53 to 13)	-35 (-63 to -7)	0.00052

¹Medians and ranges of Δ-values are presented. Δ-values are calculated by the difference between preoperative value and the maximum postoperative value or postoperative nadir. P-values were calculated, comparing the Δ-value of each serum marker among the different resection groups (One-way Anova analysis of variance);

²Denote statistical significance among resections in the group of anatomical, atypical, and combinated resections;

³Variable is presented as median value and range of postoperative maximum, since no preoperative values were available;

⁴P-value was calculated, comparing postoperatively determined ammonia levels (maximum) among the different resection groups (One-way Anova analysis of variance). ASAT: Aspartate transaminase; ALAT: Alanine aminotransferase.