Diagnostic non-invasive model of large risky esophageal varices in cirrhotic hepatitis C virus patients

Table 1 Patients characteristicsn n (%)

Variables	All patients (n = 124)	No varices (n = 50)	Small varices (n = 28)	Large varices (n = 46)	P value
Age, mean ± SD	56.52 ± 5.759	57.28 ± 4.513	58.57 ± 3.072	54.43 ± 7.423	0.005
Gender
Female	52 (41.9)	24 (48.0)	12 (42.9)	16 (34.8)	0.421
Male	72 (58.1)	26 (52)	16 (57.1)	30 (65.2)
Laboratory data (mean ± SD)
Serumalbumin (g/dL)	3.329 ± 0.43	3.452 ± 0.404	3.271 ± 0.352	3.229 ± 0.474	0.028
Serum bilirubin (mg/dL)	1.312 ± 0.572	1.093 ± 0.534	1.414 ± 0.591	1.489 ± 0.532	0.001
INR	1.326 ± 0.238	1.249 ± 0.225	1.431 ± 0.24	1.347 ± 0.226	0.003
Serum creatinine (mg/dL)	0.999 ± 0.179	0.956 ± 0.169	0.994 ± 0.178	1.047 ± 0.180	0.044
AST (IU/L)	68.00 ± 40.086	65.84 ± 44.072	63.71 ± 22.993	72.96 ± 43.797	0.561
ALT (IU/L)	55.18 ± 23.607	51.84 ± 19.844	57.43 ± 24.848	57.43 ± 26.519	0.436
Platelet count (cells/mm3)	152.94 ± 22.012	145.96 ± 20.833	156.5 ± 27.941	1548.35 ± 17.071	0.001
AFP (ng/mL)	2.687 ± 2.687	3.646 ± 60.527	5.868 ± 1.854	3.274 ± 811.945	0.064
Clinical data
Spleen size (mm)	152.94 ± 22.012	145.96 ± 20.833	156.5 ± 27.941	158.35 ± 17.071	0.013
Presence of ascites					0.017
Mild (respo-nsive)	34 (27.5)	6 (12)	8 (28.5)	20 (43.4)
No	90 (72.6)	44 (88)	20 (71.4)	26 (56.5)
MELD score (mean ± SD)	1.103 ± 2.828	9.852 ± 2.480	1.2 ± 2.55	1.171 ± 2.942	0.001
History of encepha-lopathy
No	124 (100)	50 (100)	28 (100)	46 (100)
Yes	0 (0)	0 (0)	0 (0)	0 (0)
Child Pugh Classification
A	78 (62.9)	42 (84.3)	18 (64.3)	18 (39.1)	0.001
B	46 (37.1)	8 (16)	10 (35.7)	28 (60.9)

AST: Aspartate transaminase; ALT: Alanine aminotransferase; AFP: Alpha fetal protein.