Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis

Table 1 Demographic, clinical and biochemical characteristics of the non-alcoholic fatty liver disease patients

	Steatosis (n = 9)	NASH (n = 93)	P value
Age	55.11 ± 10.3	56.51 ± 10.13	0.692
Men/women (n)	0% (0)/100% (9)	34.41% (32)/65.59% (61)	0.04a
Type 2 diabetes (n)	33.33% (2)	60.67% (54)	0.224
Dyslipidaemia (n)	83.33% (5)	79.78% (71)	1
High-blood pressure (n)	66.67% (4)	64.04% (89)	1
BMI	31.28 ± 5.79	31.25 ± 5.93	0.969
Fasting glucose (mg/dL)	91.71 ± 9.2	123.14 ± 48.28	0.033a
Insulin (μU/mL)	12.44 ± 4.2	19.92 ± 13.29	0.102
HOMA-IR value ≥ 2.5	57.14%	83.53%	0.115
AST (U/L)	25.14 ± 6.89	38.8 ± 37.99	0.159
ALT (U/L)	40 ± 16.74	50.65 ± 54.99	0.934
GGT (U/L)	56.57 ± 59.9	87.36 ± 96.33	0.185
Total cholesterol (mg/dL)	203.29 ± 54.39	195.31 ± 45.71	0.863
HDL (mg/dL)	53 ± 6.58	46.15 ± 13.42	0.067
LDL (mg/dL)	124.14 ± 51.87	114.89 ± 39.74	0.72
Triglycerides (mg/dL)	130.43 ± 59.19	167.25 ± 82.02	0.258

^aP value < 0.05. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; HDL: High-density lipoprotein; HOMA-IR: Homeostatic Model of Assessment; LDL: Low-density lipoprotein; GGT: Gamma glutamyl transferase; NASH: Nonalcoholic steatohepatitis.