Interplay between microRNA-17-5p, insulin-like growth factor-II through binding protein-3 in hepatocellular carcinoma

Table 4 Predicted target region-seed sequence binding for miR-17-5p on the 3’UTR of insulin-like growth factor binding protein-3

Target region	hsa-miR-17-5p (seed sequence) binding to IGFBP-3(target sequence)	Target sequence position on3’UTR of IGFBP-3	6mer/7mer/8mer
Region 1	miR-17-5p 3’gaUGGACGUG-ACAUUCGUGAAAc 5’ | | : | | : | | | | | | | | | IGFBP-3 5’aaACUUGAGCAUCUUUUCACUUUc 3’	196-204	6mer
Region 2	miR-17-5p 3’GAUGGAC- GUGACAUUCGUGAAAC 5’ | ||__ | | || |___ | | | | || IGFBP-3 5’ CGGCCGACCACUG-----------ACUUUG 3’	335-343	6mer

IGFBP-3: Insulin-like growth factor binding protein-3; miR-17-5p: MicroRNA-17-5p.