Cholesterol metabolism in cholestatic liver disease and liver transplantation: From molecular mechanisms to clinical implications

Figure 1 From the gut to the circulation: An overview of the pathways involved in cholesterol absorption and synthesis. IDL: Intermediate density lipoprotein; HDL: High density lipoprotein; LDL: Low density lipoprotein; VLDL: Very low density lipoprotein; NPC1L1: Niemann-Pick C1 like 1; ABCG5: Adenosine triphosphate-binding cassette transporter G5 heterodimer; HMGCoA: 3-hydroxy-3-methyl-glutaryl CoA; FXR: Farnesoid X receptor.