Review
Copyright ©The Author(s) 2016.
World J Hepatol. Jul 28, 2016; 8(21): 891-901
Published online Jul 28, 2016. doi: 10.4254/wjh.v8.i21.891
Table 1 Current diagnostic criteria for acute kidney injury in general population
RIFLE criteria[27]AKIN criteria[28]KDIGO criteria[29]
Diagnostic criteriaIncrease in SCr to ≥ 1.5 times baseline, within 7 d; or GFR decrease > 25%; or urine volume < 0.5 mL/kg per hour for 6 hIncrease in sCr by ≥ 0.3 mg/dL (26.5 mmol/L) within 48 h; or increase in sCr ≥ 1.5 times baseline within 48 h; or urine volume < 0.5 mL/kg per hour for 6 hIncrease in sCr by ≥ 0.3 mg/dL (26.5 mmol/L) within 48 h; or increase in SCr to ≥ 1.5 times baseline, which is known or presumed to have occurred within the prior 7 d; or urine volume < 0.5 mL/kg per hour for 6 h
Risk: sCr increase 1.5-1.9 times baseline; or GFR decrease 25%-50%; or urine output < 0.5 mL/kg per hour for 6 hStage 1: sCr increase 1.5-1.9 times baseline; or sCr increase ≥ 0.3 mg/dL (26.5 mmol/L); or urine output < 0.5 mL/kg per hour for 6 hStage 1: sCr increase 1.5-1.9 times baseline; or sCr increase ≥ 0.3 mg/dL (26.5 mmol/L); or urine output < 0.5 mL/kg per hour for 6-12 h
StagingInjury: sCr increase 2.0-2.9 times baseline; or GFR decrease 50%-75%; or urine output < 0.5 mL/kg per hour for 12 hStage 2: sCr increase 2.0-2.9 times baseline; or urine output < 0.5 mL/kg per hour for 12 hStage 2: sCr increase 2.0-2.9 times baseline; or urine output < 0.5 mL/kg per hour for ≥ 12 h
Failure: sCr increase ≥ 3.0 times baseline: or GFR decrease 50%-75%; or sCr increase ≥ 4.0 mg/dL (353.6 mmol/L) with an acute increase of at least 0.5 mg/dL (44 mmol/L); or urine output < 0.3 mL/kg per hour for ≥ 24 h; or anuria for ≥ 12 hStage 3: sCr increase 3.0 times baseline; or sCr increase ≥ 4.0 mg/dL (353.6 mmol/L) with an acute increase of at least 0.5 mg/dL (44 mmol/L); or urine output < 0.3 mL/kg per hour for ≥ 24 h; or anuria for ≥ 12 hStage 3: sCr increase 3.0 times baseline; or sCr increase to ≥ 4.0 mg/dL (353.6 mmol/L); or initiation of renal replacement therapy; or urine output < 0.3 mL/kg per hour for ≥ 24 h; or Anuria for ≥ 12 h