Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B

Table 5 Comparing area under the receiver operating characteristic curve of acoustic radiation force impulse/acoustic radiation force impulse + aspartate aminotransferase to platelet ratio index/acoustic radiation force impulse + Forns index/acoustic radiation force impulse + aspartate aminotransferase to platelet ratio index + Forns index in patients with fibrosis stage ≥ F2

Comparison	AUROC	Difference	95%CI		Z	P value
			Lower limit	Upper limit
ARFI	0.913	0.027	0.008	0.046	2.770	0.006
ARFI + APRI	0.940
ARFI	0.913	0.020	0.001	0.040	2.091	0.037
ARFI + Forns index	0.933
ARFI	0.913	0.031	0.010	0.053	2.893	0.004
ARFI + APRI + Forns index	0.944
ARFI + APRI	0.940	0.007	-0.011	0.025	0.728	0.466
ARFI + Forns index	0.933
ARFI + APRI	0.940	0.005	-0.005	0.014	0.958	0.338
ARFI + APRI + Forns index	0.944
ARFI + Forns index	0.933	0.011	-0.001	0.023	1.789	0.074
ARFI + APRI + Forns index	0.944

AUROC: Area under the receiver operating characteristic curve; ARFI: Acoustic radiation force impulse; APRI: Aspartate aminotransferase to platelet ratio index.