Copyright
©The Author(s) 2016.
World J Hepatol. May 18, 2016; 8(14): 616-624
Published online May 18, 2016. doi: 10.4254/wjh.v8.i14.616
Published online May 18, 2016. doi: 10.4254/wjh.v8.i14.616
Table 3 Cut-off values of acoustic radiation force impulse and aspartate aminotransferase to platelet ratio index for the diagnosis of liver fibrosis (95%CI)
≥ F1 | ≥ F2 | ≥ F3 | F4 | |
ARFI | ||||
Cut-off (m/s) | 1.26 | 1.29 | 1.43 | 1.62 |
Sensitivity | 76.2% (69.80-81.90) | 83.6% (77.10-88.90) | 82.3% (74.00-88.80) | 90.7% (79.70-96.90) |
Specificity | 95.0% (83.10-99.40) | 90.1% (89.50-97.60) | 89.5% (83.00-94.10) | 92.2% (87.40-95.60) |
PPV | 99.1% (96.20-99.90) | 94.5% (91.90-99.10) | 86.9% (79.10-92.70) | 76.0% (64.40-86.30) |
NPV | 35.9% (22.50-47.40) | 73.0% (63.10-81.40) | 85.6% (78.60-91.00) | 97.2% (93.70-99.10) |
AUROC | 0.90 (0.86-0.94)a | 0.91 (0.87-0.95)a | 0.94 (0.90-0.96)a | 0.96 (0.93-0.98)a |
APRI | ||||
Cut-off (m/s) | 0.30 | 0.41 | 0.49 | 0.44 |
Sensitivity | 84.0% (78.20-88.70) | 68.5% (60.80-75.50) | 63.7% (54.10-72.60) | 83.3% (70.70-92.10) |
Specificity | 85.0% (70.20-94.30) | 82.7% (72.70-90.20) | 79.7% (71.90-86.20) | 67.2% (70.10-73.80) |
PPV | 97.6% (94.20-99.30) | 89.0% (82.20-93.80) | 72.8% (62.90-81.20) | 41.7% (32.30-51.60) |
NPV | 42.7% (30.00-56.10) | 56.3% (46.80-65.40) | 72.1% (64.00-79.20) | 93.5% (87.90-97.00) |
AUROC | 0.92 (0.88-0.95)a | 0.84 (0.79-0.89)a | 0.79 (0.73-0.84)a | 0.82 (0.76-0.86)a |
- Citation: Dong CF, Xiao J, Shan LB, Li HY, Xiong YJ, Yang GL, Liu J, Yao SM, Li SX, Le XH, Yuan J, Zhou BP, Tipoe GL, Liu YX. Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B. World J Hepatol 2016; 8(14): 616-624
- URL: https://www.wjgnet.com/1948-5182/full/v8/i14/616.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i14.616