Predictors of mortality after transjugular portosystemic shunt

doi:10.4254/wjh.v8.i11.520

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Apr 18, 2016 (publication date) through Nov 5, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Apr 18, 2016; 8(11): 520-529
Published online Apr 18, 2016. doi: 10.4254/wjh.v8.i11.520

Table 4 Predictors of long term mortality in univariate Cox survival analysis

Variables	HR	95%CI	P
Age (per 1 yr)	1.02	1.01-1.03	0.001^b
HCV (ETOH reference)	1.45	1.03-2.04	0.03^a
Splenectomy (yes)	3.32	1.36-8.10	0.008^b
CHF (yes)	1.32	1.01-1.74	0.04^a
Hypothyroidism (yes)	1.20	1.00-1.42	0.04^a
CKD on HD (yes)	1.56	1.17-2.06	0.002^b
Portal vein pressure before TIPS (per 1 mmHg)	1.03	1.01-1.04	0.008^b
RA pressure before TIPS (per 1 mmHg)	1.03	1.01-1.06	0.01^a
RA pressure after TIPS (per 1 mmHg)	1.03	1.00-1.05	0.02^a
MELD score (per 1 unit)	1.07	1.05-1.09	< 0.001^b
Albumin (per 1 mg/dL)	0.70	0.58-0.84	< 0.001^b
Billirubin (per 1 mg/dL)	1.05	1.03-1.07	< 0.001^b
INR (per 1 unit change)	1.30	1.07-1.60	0.01^a
Creatinine (per 1 mg/dL)	1.26	1.14-1.39	< 0.001^b
CTP category B (reference A)	1.98	1.24-3.18	0.004^b
CTP category C (reference A)	3.02	1.85-4.94	< 0.001^b
EF echocardiogram pre TIPS (per 1% increase)	0.98	0.95-1.00	0.04^a
RVSP pre TIPS (per 1 mmHg increase)	1.02	1.01-1.04	0.005^b
Moderate RV dysfunction (normal RV reference)	2.84	1.18-6.85	0.02^a
EF post TIPS (per 1% increase)	0.98	0.96-1.00	0.03^a
RVSP post TIPS (per 1 mmHg increment)	1.02	1.01-1.04	0.01^a

^aP < 0.05;

^bP < 0.01. CHF: Congestive heart failure; CKD: Chronic kidney disease; CTP: Child turcotte pugh; EF: Ejection fraction; HCV: Hepatitis C virus; HD: Hemodialysis; HR: Hazard ratio; MELD: Model for End stage Liver Disease; RA: Right atrium; RV: Right ventricle; RVSP: Right ventricular systolic pressure; TIPS: Transjugular intrahepatic portosystemic shunt; INR: International normalized ratio; ETOH: Alcoholic etiology.

Citation: Ascha M, Abuqayyas S, Hanouneh I, Alkukhun L, Sands M, Dweik RA, Tonelli AR. Predictors of mortality after transjugular portosystemic shunt. World J Hepatol 2016; 8(11): 520-529
URL: https://www.wjgnet.com/1948-5182/full/v8/i11/520.htm
DOI: https://dx.doi.org/10.4254/wjh.v8.i11.520