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©The Author(s) 2016.
World J Hepatol. Apr 8, 2016; 8(10): 499-508
Published online Apr 8, 2016. doi: 10.4254/wjh.v8.i10.499
Published online Apr 8, 2016. doi: 10.4254/wjh.v8.i10.499
Table 4 Utility of biomarkers in differentiating cirrhosis with alcoholic hepatitis from cirrhosis with acute decompensation from etiologies other than alcohol: Receiver operating characteristics analysis
Biomarker | AUC (95%CI) |
Citrulline and betaine | 0.835 (0.747, 0.978) |
Betaine and phenylalanine | 0.810 (0.684, 0.937) |
Citrulline and phenylalanine | 0.758 (0.609, 0.907) |
Citrulline | 0.758 (0.610, 0.907) |
Betaine | 0.732 (0.588, 0.877) |
Phenylalanine | 0.715 (0.567, 0.863) |
Crotonobetaine | 0.663 (0.498, 0.827) |
Tyrosine | 0.650 (0.484, 0.817) |
Butyrobetaine | 0.649 (0.489, 0.808) |
Creatinine | 0.645 (0.486, 0.805) |
Octenoyl-carnitine | 0.631 (0.488, 0.774) |
Propionyl-carnitine | 0.620 (0.453, 0.787) |
Homocitrulline | 0.618 (0.457, 0.779) |
Trimethyl-lysine | 0.616 (0.447, 0.784) |
Butyryl-carnitine | 0.615 (0.451, 0.778) |
Pentanoyl-carnitine | 0.613 (0.455, 0.771) |
Choline | 0.597 (0.432, 0.762) |
Valine | 0.588 (0.424, 0.752) |
Lysine | 0.559 (0.393, 0.725) |
Methyl-lysine | 0.552 (0.383, 0.721) |
Iso-leucine | 0.548 (0.379, 0.716) |
Acetyl-carnitine | 0.543 (0.375, 0.710) |
Hexanoyl-carnitine | 0.529 (0.362, 0.696) |
TMAO | 0.521 (0.347, 0.695) |
Argine | 0.507 (0.339, 0.675) |
ADMA | 0.481 (0.314, 0.647) |
Leucine | 0.477 (0.309, 0.644) |
Carnitine | 0.470 (0.301, 0.638) |
MMA | 0.453 (0.286, 0.620) |
SDMA | 0.447 (0.277, 0.617) |
Dimethyl-lysine | 0.417 (0.243, 0.592) |
Ornithine | 0.351 (0.186, 0.517) |
- Citation: Ascha M, Wang Z, Ascha MS, Dweik R, Zein NN, Grove D, Brown JM, Marshall S, Lopez R, Hanouneh IA. Metabolomics studies identify novel diagnostic and prognostic indicators in patients with alcoholic hepatitis. World J Hepatol 2016; 8(10): 499-508
- URL: https://www.wjgnet.com/1948-5182/full/v8/i10/499.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i10.499