Selection of patients with hepatocellular carcinoma for liver transplantation: Past and future

Table 5 Japanese combined morphological/biological selection criteria for living-donor liver transplant

Ref.	Parameters					Importance: Limits for LDLT
	Value	1p	2p	3p	4p
Yang et al[67]	T size (cm)	≤ 3	3.1-5	5.1-6.5	> 6.5	Patients with 3-6 points are transplantable
	of tumors	1	2-3	4-5	> 5 or 6	Those with 7-12 points are not transplantable
	AFP (ng/mL)	< 20	20-200	200.1-1.000	< 1.000
Akamatsu et al[68]	Up to 5 nodules					Upper limit for LDLT
	Maximum diameter ≤ 5
Kaido et al[69]	Less that 10 nodules, all < 5 cm					Upper limit for LDLT
	DCP < 400 mAu/mL
Shirabe et al[70]	n of nodules: No limit					Upper limit for LDLT
	Maximun diameter: < 5 cm
	DCP < 300 mAu/mL

AFP: Alpha fetoprotein; DCP: Des-gamma carboxy prothrombin; LDLT: Living-donor liver transplant.