Acute kidney injury in patients with chronic liver disease

Table 2 Diagnostic criteria of type 1 hepatorenal syndrome porposed by the international ascites club[25]

Cirrhosis with ascites

SCr > 1.5 mg/dL (133 μmol/L)

Doubling of basal SCr to a level greater than 2.5 mg/dL (226 μmol/L) in less than 2 wk

No improvement in SCr (decrease to 1.5 mg/dL or less) after at least 2 d of diuretic withdrawal and expansion of plasma volume with albumin (1 g/kg body weight/d up to a maximum of 100 g/d)

Absence of shock

No current or recent treatment with nephrotoxic drugs or vasodilators

Absence of parenchymal kidney disease as indicated by proteinuria > 0.5 g/d, hematuria (> 50 red blood cells per high-power field), or abnormal renal ultrasonography

SCr: Serum creatinine.