Incidence, risk factors and outcome of de novo tumors in liver transplant recipients focusing on alcoholic cirrhosis

Table 1 Overall incidence of de novo tumors after liver transplantation n (%)

Ref.	No. OLT	Follow-up period	Time from OLT-DNT	Pts with DNT	DNT incidence	Overall SIR
Jonas et al[18]	458	50/22 mo	43 mo	33	34 (7.2)	-
Jain et al[1]	1000	78 mo	36 mo	57	58 (5.7)	7.6 (UAD)
Kelly et al[33]	888	29.3 ± 25.2 mo	24 ± 16.8 mo	39	43 (4.8)	-
Peyrègne et al[8]	251	50.5 mo	24.3 mo	11	12 (4.8)	-
Galve et al[34]	1827	20 ± 18 mo	30.7 ± 22 mo	70	70 (3.8)	-
Sheiner et al[2]	121	499 persons/yr	19.2 mo	18	19 (15.7)	3.9
Haagsma et al[5]	174	61 mo	-	21	23 (13.2)	-
Xiol et al[25]	137	69 mo	12-104 mo	22	30 (21.9)	-
Jiménez et al[35]	505	8-168 mo	47.8 mo	57	62 (12.2)	-
Saigal et al[26]	1140	69 mo	45 mo	30	30 (2.6)	-
Sanchez et al[6]	1421	67 mo	-	125	125 (8.8)	-
Benlloch et al[11]	772	51 mo	40 mo	41	41 (5.3)	-
Herrero et al[36]	187	65 mo	49.5 mo	49	63 (33.6)	-
Oo et al[12]	1778	-	57 mo	141	141 (7.9)	2.07
Aberg et al[7]	540	3222 persons/yr	61 mo	47	50 (9.2)	2.59
Jiang et al[17]	2034	-	42.2 ± 33.8 mo	113	113 (5.5)	2.5
Baccarani et al[37]	417	81.6 mo	51 mo	43	43 (10.3)	2.7
Chatrath et al[38]	534	68 ± 38.4 mo	48 ± 26.4 mo	73	80 (14.9)	3.1
Collett et al[39]	6846	-	-	-	-	2.2
Tjon et al[40]	385	> 4 mo	-	50	66 (17.1)	2.2
Engels et al[41]	6291	-	-	-	-	2.2
Krynitz et al[42]	1221	61.2 mo	-	150	150 (12.3)	3.4
Sampaio et al[43]	43216	-	31.2 mo	1923	1923 (4.4)	-
Ettorre et al[32]	1675	62.4 mo	38.4 mo	98	100 (5.9)	1.4
Schrem et al[16]	2000	-	82.7 mo	115	120 (6)	1.94
Wimmer et al[44]	609	57.3 mo	68.4 ± 44.4 mo	71	87 (14.3)	-

OLT: Orthotopic liver transplantation; DNT: De novo tumors; UAD: Upper aerodigestive tumor.