Liver cirrhosis in hepatic vena cava syndrome (or membranous obstruction of inferior vena cava)

Table 2 Comparison of frequency of acute exacerbations in hepatic vena cava syndrome: Among patients who did and did not develop liver cirrhosis and hepatocellular carcinoma¹

	Incidence of AE	P value
Who did not develop LC/HCC	3.2 ± 3.2
Patient who developed LC	6.5 ± 4.5	0.017
Patients who developed HCC	11.5 + 3.01	< 0.001
56 patients of HVCS seen in the period 1990-1997
Followed up for 14.8 ± 9 yr
LC developed in 44 (78.5%). HCC developed in 6 (10.7%)

¹Quarter of the AE in HCC group was severe. Severe AE: Development of ascites due to HVOO. Modified from Shrestha et al[45]. HVCS: Hepatic vena cava syndrome; HCC: Hepatocellular carcinoma; AE: Acute exacerbation; LC: Liver cirrhosis; HVOO: Hepatic venous outflow obstruction.