Host cellular microRNA involvement in the control of hepatitis B virus gene expression and replication

Table 1 Direct interactions of microRNAs with hepatitis C virus and hepatitis B virus RNA

Host miRNA	Binding location	Function	Expression	Ref.
miR-20a	X and polymerase	Inhibits HBV replication	Up	[23]
miR-92a-1	X and polymerase	Inhibits HBV replication	Up	[23]
miR-122	Core and DNA polymerase	Inhibits HBV replication	Down	[20]
miR-125a-5p	HBsAg	Inhibits HBV replication	Up	[22]
miR-199a- 3p	HBsAg	Inhibits HBV replication	Up	[21]
miR-205	HBx	Suppresses HBx production	Down	[25]
miR-210	PreS1	Inhibits HBV replication	Up	[21]
miR-1231	HBx/HB core	Inhibits HBV replication	Up	[26]

HBsAg: Hepatitis B surface antigens; HBV: Hepatitis B virus; HBx: HBV X.