Staging systems for hepatocellular carcinoma: Current status and future perspectives

Table 11 Advanced liver cancer prognostic system

Characteristics		Points
Ascites	Yes	2
	No	0
Abdominal pain	Yes	2
	No	0
Weight loss	Yes	2
	No	0
Child-Pugh grade	A	0
	B	2
	C	5
ALP (IU/L)	> 200	3
	≤ 200	0
Total bilirubin (mmol/L)	> 50	3
	33-50	1
	≤ 33	0
Urea (mmol/L)	> 8.9	2
	≤ 8.9	0
Portal vein thrombosis	Yes	3
	No	0
Tumor size	Diffuse	4
	> 5 cm	3
	≤ 5 cm	0
Lung metastases	Yes	3
	No	0
AFP (ng/mL)	> 400	4
	≤ 400	0
Prognosis	Score	3-mo survival rate
Good	0-2	> 0.81
	3-6	0.72-0.8
	7-8	0.66-0.69
Intermediate	9	0.63
	10-12	0.51-0.59
	13-14	0.42-0.47
	15	0.38
Poor	16	0.33
	17-19	0.21-0.29
	20-22	0.1-0.17
	≥ 23	< 0.1

AFP: Alpha-fetoprotein; ALP: Alkaline phosphatase.